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Garlic Parmesan Chicken Penne in Creamy Cajun Three-Cheese Sauce

Garlic Parmesan Chicken Penne in Creamy Cajun Three-Cheese Sauce

Garlic Parmesan Chicken Penne in Creamy Cajun Three-Cheese Sauce is a mouthwatering pasta dish that combines the rich flavors of garlic and cheese with a delightful Cajun kick. This creamy, cheesy meal is perfect for busy weeknights, taking just 30 minutes to prepare from start to finish. With tender chicken pieces enveloped in a luscious sauce and served over al dente penne, this comforting recipe is sure to impress at family dinners or casual gatherings. Easy cleanup makes it even more appealing, as everything cooks in a single skillet.

  • Total Time: 30 minutes
  • Yield: Serves 4

Ingredients

Scale
  • 1 lb boneless, skinless chicken breasts
  • 12 oz penne pasta
  • 2 tablespoons olive oil
  • 4 cloves garlic
  • 1 ½ cups heavy cream
  • ½ cup shredded mozzarella cheese
  • ½ cup shredded cheddar cheese
  • ½ cup grated Parmesan cheese
  • Cajun seasoning

Instructions

  1. Cook penne pasta according to package instructions until al dente. Drain and set aside.
  2. Season chicken with Cajun seasoning, salt, and pepper.
  3. In a large skillet over medium-high heat, heat olive oil and sauté chicken until golden brown (6–8 minutes). Remove chicken and set aside.
  4. In the same skillet, melt butter over medium heat, add minced garlic, and sauté until fragrant (1–2 minutes).
  5. Stir in heavy cream and chicken broth; bring to a gentle simmer.
  6. Add mozzarella, cheddar, and Parmesan cheeses; stir until melted.
  7. Return cooked chicken to the skillet; toss to coat with sauce.
  8. Add cooked penne pasta; mix until fully coated.
  9. Garnish with fresh parsley before serving.
  • Author: Natalia
  • Prep Time: 10 minutes
  • Cook Time: 20 minutes
  • Category: Main
  • Method: Sautéing
  • Cuisine: Cajun

Nutrition

  • Serving Size: 1 plate (approximately 350g)
  • Calories: 720
  • Sugar: 3g
  • Sodium: 980mg
  • Fat: 45g
  • Saturated Fat: 20g
  • Unsaturated Fat: 23g
  • Trans Fat: 0g
  • Carbohydrates: 54g
  • Fiber: 3g
  • Protein: 38g
  • Cholesterol: 150mg

Keywords: Use fresh ingredients for optimal flavor. Adjust Cajun seasoning based on your spice tolerance. Feel free to substitute the chicken with sautéed vegetables for a vegetarian option.